62-LQP-JABS 20260903105624 Lumina Quest Publishing m.arslansohail@gmail.com Lumina Quest Publishing Journal of Advanced Biological Sciences J. Adv. Biol. Sci. 3134-8823 10.66590/jabs https://lquestpub.com/archives.php?journal=journal-of-advanced-biological-sciences 12 30 2025 12 30 2025 2 2 10.66590/jabs20250202 https://lquestpub.com/articles-list.php?journal=journal-of-advanced-biological-sciences&volume=2&issue=2 Prevention and Management of Extravasation Associated with Non-Cytotoxic Agents: A Review Study Bat Shatha R. Zaidan Intravenous medication administration is associated with a higher risk of complications and medication errors compared with other routes of drug delivery. Such errors may negatively affect both patients and healthcare professionals, particularly nurses responsible for medication administration. Although only a small proportion of these errors result in severe patient outcomes, even minor incidents may lead to significant physical, psychological and professional consequences for nursing staff. Phlebitis and extravasation are among the most common adverse complications associated with intravenous therapy. Nurses play a critical role in monitoring intravenous medication administration, alleviating patient discomfort and preventing the occurrence of extravasation and related complications through the application of appropriate clinical techniques and preventive strategies, thereby improving patient safety and quality of life. The incidence of extravasation in adults has been estimated to range from 0.1% to 6%. Several reports suggest that the frequency of extravasation events has decreased in recent years due to improvements in infusion technologies, early detection of medication leakage, adherence to safe administration protocols and enhanced staff education and training regarding prevention and management strategies. Nevertheless, despite the implementation of preventive measures, including standardized administration procedures, institutional regulations and continuous healthcare staff education, extravasation remains a clinically important complication of intravenous therapy. 12 30 2025 12 30 2025 16 19 10.66590/jabs2025020203 https://lquestpub.com/article/10.66590/jabs2025020203